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The second response cycle in NO synthesis includes O2 binding to ferrous NOS to form the Fe, IIO2 intermediate, followed by oxidation of NOHA to generate ferric enzyme, NO, citrulline, and water as items (Fig. 9) - circular dichroism. As drawn in Fig - helpful hints https://www.brownbook.net/business/52441542/olis-clarity/. 9, the response might also include electron transfer from H4B to the Fe, IIO2 intermediate

l9 As displayed in Fig. 9, this could be due to the fact that the H4B radical acts as an electron sink in a later point in the response, so as to allow NOS to, Fig. 9. A design for NORA oxidation by NOSoxy in the single turnover reaction. Oxygen binds to the ferrous protein to form the Fe, IIO2 types, which upon receiving an electron from H4B forms a putative hemeperoxo intermediate that responds with NOHA.